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Estrogen HRT Can Limit Plaque Accumulation In Arteries, Study Says

November 21st, 2008 · No Comments
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Estrogen can rein in essentially the silt of plaque bordered by the artery of women in their 50s, according to a sanctum published on apex of Thursday in the New England Journal of Medicine, the Milwaukee Journal Sentinel reports (Newson, Milwaukee Journal Sentinel, 6/20). For the study, JoAnn Manson, chief of preventive prescription at Brigham and Women’s Hospital in Boston, and colleagues pore over a subset of women who participate in the Women’s Cialis Professional Initiative (Rubin, USA Today, 6/21).

The 1,064 participant be ages 50 to 59 and hold undergone surgically pay off menopause through a hysterectomy when the study start off. Half of study participants race Wyeth’s estrogen dose Premarin and moderately took a placebo (Maugh, Los Angeles Times, 6/21). Study participants took estrogen or a placebo in support of 7.5 years, after which they undergo cardiac scan to revise the plane of accumulation of plaque in their arteries (Stobbe, AP/Philadelphia Inquirer, 6/21).

According to the study, participants who took estrogen were 30% to 40% minor amount plausible than those who took a placebo to have big amounts of plaque in their arteries, an indication of heart ambush stake (Emery, Reuters, 6/21). In appendix, participants who took estrogen on a perched spring were 60% less likely than those who took a placebo to have large amounts of plaque in their arteries, the study found (Parker-Pope, Wall Street Journal, 6/21).

However, participants who took estrogen had a complex risk for button than those who took a placebo, according to the study (AP/Philadelphia Inquirer, 6/21).

Comments Manson said the study fulfil not bracket for that women should take estrogen to tire out their risk for heart attack (Wall Street Journal, 6/21). “Hormone analysis should not be in earlier times of interest for the suggest aim of exclude cardiovascular illness in the red to other stigma on risk, and it should be thicken to remedy of menopausal symptom at the lowest dose for the shortest duration vital,” Manson said (Reuters, 6/21). Elizabeth Nabel, superintendent of the National Heart, Lung and Blood Institute, which supporter the study, said that the grades “do not alter the substantial recommendation that, when hormone therapy be used for menopausal symptoms, it should personal be taken at the smallest dose and for the shortest period possible” and “never be used to prevent heart disease.” Manson said that the results of the study “provide quite a lot of added reassurance for women who have be deny themselves relief” from scorching flash and other symptoms of menopause (Los Angeles Times, 6/21). A medical practitioner for Wyeth said that lots women should begin to take estrogen after they depose menopause and aver treatment indefinitely (Reuters/Washington Times, 6/21).

An abstract of the study is untaken online.

NPR’s “All Things Considered” on Thursday story on the study (Knox, “All Things Considered,” NPR, 6/21). Audio and a partial transcript of the segment be available online.

“Reprinted near okay from You can outlook the complete Kaiser Daily Cialis Professional Policy Report, prod the archives, or suggestion wakeful for email distribution at The Kaiser Daily Cialis Professional Policy Report is published for www.bestdrugsnow.com, a single employ of The Henry J. Kaiser Family Foundation . © 2005 Advisory Board Company and Kaiser Family Foundation. All rights smart.

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